The main difference that I have experienced (and like the other commenters stated, everyone is different and your dr is the one to talk to about which works for you) is that Vyvanse helped me lose weight on top of helping with the ADHD. It was the first medication I took. Now I'm on Adderall, only because my insurance won't cover Vyvance. It doesn't seem to work as well as the Vyvance but my wallet likes it better 😁

Which one works best for you? I’m currently taking Ritalin 15mg *2~3 /day, wandering whether I should change to Vyvance.

NUMO ADHDNUMO
ADHD

Andrew Huberman just compared Adderall Vyvance Ritalin etc.